Vaccinators wearing protective masks as they get their temperature checked, during an anti-polio campaign in Karachi, Pakistan.
Vaccinators wearing protective masks as they get their temperature checked, during an anti-polio campaign in Karachi, Pakistan. Credit: REUTERS/Akhtar Soomro

Fall is everywhere, from colorful leaves landing on lawns to reminders to get a flu shot to the powerful piece in this month’s Smithsonian magazine on the fear and devastation wrought by diphtheria until an effective vaccine was found. The author notes that “Despite all the progress preventing and treating the disease, diphtheria has not been eradicated and still flares up around the world.” As we fight our way through the COVID-19 pandemic, we can take some comfort from the success of one global vaccination effort: the fight to eradicate polio. Oct. 24 is World Polio Day and there is a real chance that polio will soon be eradicated, though there is still work to be done.

After the World Health Organization (WHO) declared the African region free of the wild poliovirus last August, the focus turned to Pakistan and Afghanistan, the last two polio-endemic countries. The concern was that the COVID-19 pandemic had made it difficult to conduct polio immunizations for several months and there was fear that wild polio would rebound in both countries. After a brief pause in early 2020, vaccinators began polio immunizations again in both countries, using new protocols to avoid the risks of transmitting COVID-19 while protecting children from polio. These protocols involved masking the vaccinators and providing masks to families, frequently using hand sanitizer, conducting vaccinations outdoors whenever possible, and asking vaccinators to double as educators and communicate about the best ways to stop the spread of COVID-19.

During the first eight months of 2021, just one case of wild polio was reported in each country, though there are still several months left in the year and some regions of Afghanistan have been difficult to access. Nevertheless, the polio program has operated for many years in both countries amid challenging circumstances and critical work will continue.

This is good news in a campaign that is entering its 33rd year. When Rotary International, WHO, UNICEF and the U.S. Centers for Disease Control and Prevention first launched the Global Polio Eradication Initiative (GPEI) in 1988, there were over 350,000 cases of polio in 125 countries. Polio had been eliminated in the United States and much of Europe, but other regions had never been able to control the virus effectively. In succession, regions of the world were certified polio-free after working to reach children in rural areas. There were challenges, including the logistics of getting into isolated villages with poor roads, but solutions were found, even if it meant that vaccinators would have to pedal bicycles or hike into those areas on foot.

Today, the incidence of polio has plummeted by more than 99.9%. This is not a miracle but rather the result of enormous and sustained efforts to get safe and effective vaccines into underserved regions and into the mouths of vulnerable children. In the past 13 years, the GPEI has grown to include the Bill & Melinda Gates Foundation and Gavi, the Vaccine Alliance, both of whom have a strong presence and provide financial, logistical, and technical support.

Two major lessons have been learned over the past three-plus decades. First, global pandemics cannot be successfully combated piecemeal. For example, Tajikistan had been polio-free for several years when the country’s government reduced its efforts to reach remote villages in 2011, resulting in a resurgence of the virus as travelers came back from visits to Afghanistan, where polio was endemic. A rapid “mop up” campaign to reach transient populations was immediately launched and Tajikistan has been polio-free ever since.

Charles Adams Cogan
[image_caption]Charles Adams Cogan[/image_caption]
As long as one country has not eliminated the virus, it’s important to keep on vaccinating children in neighboring countries and across the globe. Viruses do not respect international borders, and as long as there are countries that harbor the disease there will be a danger of polio spreading to other countries.

Second, the need for clear and accurate information is critical. Since the formation of the GPEI, there have been times when rumors have circulated in many parts of the world that the vaccine is not safe, which has caused many people to refuse the vaccine. In such cases, the vaccinators have relied on the support of political and religious leaders to ensure that the communities receive the information they need from the sources they trust the most to make informed choices.

Joe Stahlmann
[image_caption]Joe Stahlmann[/image_caption]
In 1946, the Minnesota State Fair was canceled because of a polio outbreak. Uncertainty was everywhere and no effective vaccine was yet available. Now, the world is on the verge of being polio-free. At a time when the world is facing another pandemic, we should draw from the success (and learn from the challenges) of the polio eradication effort to inform our battle to protect ourselves from COVID-19.

When we speak of “us” we need to think and act globally. Sunday is also United Nations Day. If 33 years of experience in the fight to eradicate polio have taught us a lesson it is that vaccinations work. Getting the vaccines to the people in need and getting those people to accept the vaccines takes accurate messaging, patience and diplomacy. We have all of the tools and resources to lead the world again. The infrastructures put in place by the GPEI over the past 33 years are already being used for other vaccination campaigns.

Charles Adams Cogan is a French teacher at the International School of Minnesota and a mid-career MPA candidate at the Humphrey School of Public Affairs. Joe Stahlmann, the son of a polio survivor, is an architectural consultant and the past president of the Rotary Club of North St. Paul-Maplewood-Oakdale. The two are co-leaders of the Rotary District 5960 PolioPlus Team.

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3 Comments

  1. While the near global eradication of polio has been a truly remarkable accomplishment, it is a good reminder that in the early days in 1955 all the way into the 90’s, the initial rushed vaccine rollout had tragic consequences, and the reaction to the Cutter incident by the medical establishment was hardly better.

    We shouldn’t be surprised by some people’s aversion to mRNA technology, nor decisions by the medical establishment to rush the vaccine to market, especially when concerns about real and possible consequences are ignored, shamed and even censored.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383764/

    “In April 1955 more than 200 000 children in five Western and mid-Western USA states received a polio vaccine in which the process of inactivating the live virus proved to be defective. Within days there were reports of paralysis and within a month the first mass vaccination programme against polio had to be abandoned. Subsequent investigations revealed that the vaccine, manufactured by the California-based family firm of Cutter Laboratories, had caused 40 000 cases of polio, leaving 200 children with varying degrees of paralysis and killing 10.

    “The Cutter incident led to the replacement of Salk’s formaldehyde-treated vaccine with Sabin’s attenuated strain. Though Sabin’s vaccine had the advantages of being administered orally and of fostering wider `contact immunity’, it could also be re-activated by passage through the gut, resulting in occasional cases of polio (still causing paralysis in six to eight children every year in the 1980s and 1990s, when a modified Salk vaccine was re-introduced). As Offit observes, `ironically, the Cutter incident—by creating the perception among scientists and the public that Salk’s vaccine was dangerous —led in part to the development of a polio vaccine that was more dangerous’.”

    1. Your points are well-taken. It is encouraging that the production unit in Maryland that was producing vaccines last year (for COVID) was shut down after the quality of their vaccines was repeatedly compromised. Quality control is essential and you are right that the Cutter incident was a serious setback in the early days of the campaign to protect children from polio.

  2. None of these successes were/are 100% on the first try or perhaps even the 2-3 etc.
    However, I think the article clearly explains that the polio vaccine worked, as the hospitals today are not crammed with Iron Lungs, but rather ICU’s are over run with Covid cases of folks refusing to take the vaccine. And that of courses takes up beds for the normal day to day heart attacks etc. etc. etc. Point being a personal refusal (choice) to not get vaxed resulting in a covid infection, is killing other folks when the ICU bed is used to keep the Covid infected and not available for the latest heart attack, etc. ICU victim!
    https://medicine.yale.edu/news/yale-medicine-magazine/breaking-the-back-of-polio/

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